Assistant Professor
Dept. of Pharmacology & Experimental Therapeutics
Tufts University School of Medicine
136 Harrison Avenue
Boston, MA 02111
Phone: 617-636-2196
Email: Jerold.Harmatz@Tufts.edu

Research Interests:

Mr. Harmatz manages the drug trials conducted by the Division of Clinical Pharmacology within the department. He is responsible for the statistical planning and analyses required by those trials. In addition, Mr. Harmatz lectures in graduate level courses on statistics and experimental design and provides ad hoc statistical consultation.

Recent Publications:

von Moltke LL, Greenblatt DJ, Granda BW, Giancarlo GM, Duan SX, Daily JP, Harmatz JS and Shader RI. Inhibition of human Cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors. Journal of Clinical Pharmacology 41:85-91, 2001.

Cotreau MM, von Moltke LL, Harmatz JS and Greenblatt DJ. Molecular and pharmacokinetic evaluation of rat hepatic and gastrointestinal cytochrome P450 induction by tamoxifen. Pharmacology 63:210-219, 2001.

Venkatakrishnan K, von Moltke LL, Court MH, Harmatz JS, Crespi CL and Greenblatt DJ. Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches. Drug Metabolism and Disposition 28:1493-1504, 2000.

von Moltke LL, Greenblatt DJ, Giancarlo GM, Granda BW, Harmatz JS and Shader RI. Escitalopram (S-Citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-Citalopram. Drug Metabolism and Disposition 29:1102-1109, 2001.