Professor of Medicine, Pediatrics and Public Health
Faculty, Sackler Graduate Program in Pharmacology and Experimental Therapeutics
Director, Center for Global Health Research
Nutrition and Infection Unit
Jaharis 264
Tufts University School of Medicine
130 Harrison Avenue
Boston, MA 02111
Phone:  (617) 636-2431
Fax: (617) 636-3811
E-mail: patricia.hibberd@tufts.edu

Research Interests:

Dr Hibberd is an infectious disease physician, epidemiologist and clinical trialist who is focusing on the interfaces between basic and clinical research as well as clinical research and community based clinical practice, both in the US and internationally.  Specifically, her research focuses on the prevention and treatment of respiratory infections and diarrheal disease in the immunocompromised host and in children under age 5.  Current studies include testing novel strategies to eradicate antimicrobial resistance using probiotics and Phase I studies of monoclonal antibodies to prevent infectious diseases such as Clostridium difficile and complications of infection with E coli O157:H7, in collaboration with Dr Tzipori at the Tufts Cummings School of Veterinary Medicine.  Dr Hibberd also works closely with investigators in India and Peru on community based studies to prevent and treat the two most common causes of mortality in children under age 5 - pneumonia and diarrheal disease. 

Recent Publications:

Addo-Yobo E, Chisaka N, Hassan M, Hibberd P, Lozano JM, Jeena P, MacLeod WB, Maulen I, Patel A, Qazi S, Thea DM, Tuong Vy NTN. A randomized multicentre equivalency study of oral amoxicillin versus injectable penicillin in children aged 3 to 59 months with severe pneumonia. Lancet, 2004, 364:1341-8.

Hibberd PL, Patel A for the APPIS study. Challenges in the Design of Antibiotic Equivalency Studies – Multi-center Equivalency Study of Oral Amoxicillin versus Injectable Penicillin in Children aged 3-59 Months with Severe Pneumonia. Clinical Infectious Diseases, 2004, 39(4):526-31.

Khan WA, Rogers KA, Karim MM, Ahmed S, Hibberd PL, Calderwood SB, Ryan ET, Ward HD. Cryptosporidiosis Among Bangladeshi Children With Diarrhea: A Prospective Matched Case Control Study Of Clinical Features, Epidemiology And Systemic Antibody Responses. Am J Trop Med, 2004, 71:412-9.

Hibberd PL, Weiner DW. Monitoring Participant Safety in Phase I and II intervention trials – options and controversies., J Investigative Medicine, 2004, 52:446-52.

Lee GM, Salomon JA, Friedman JF, Hibberd PL, Ross-Degnan D, ScD, Zasloff E, Bediako S, Goldmann, DA. Illness transmission in the home: a possible role for alcohol based hand gels. Pediatrics, 2005 2005 115:852-60.

Curley MAQ, Hibberd PL, Fineman LD, Wypij W, Shih M-C, Thompson JE,Grant MC, Barr FE, Cvijanovich NZ, Sorce L, Luckett PM, Matthay MA, Arnold JH. Effect of Prone Positioning on Clinical Outcomes in Children With Acute Lung Injury: A Randomized Controlled Trial. JAMA. 2005;294:229-237.

Bousvaros A, Guandalini, S, Baldassano, RN, Botelho, C, Evans J, Ferry, G, Goldin, B, Hartigan, L Kugathasan, S, Levy, J, Murray, K, Oliva-Hemker, M, Rosh, J, Tolia, V, Zholudev, A; Vanderhoof, JA, Hibberd, PL. Randomized, Double-blind Trial of Lactobacillus GG Versus Placebo in Addition to Standard Maintenance Therapy for Children with Crohn's Disease. Inflammatory Bowel Diseases 2005 11(9):833-839.

Curley MAY, Arnold JH, Thompson JE, Fackler JC, Grant MJ Fineman LD, Cvijanovich N, Barr FE, Molitor-Kirsch S, Steinhorn DM, Mathhay MA, Hibberd, PL. Clinical trial design – effect of prone position on clinical outcomes in infants and children with acute respiratory distress syndrome. J Crit Care 2006, 21:23-32.

McGovern BH, Ditelberg JS, Taylor LE, Gandhi RT, Christopoulos KA, Chapman S, Schwartzapfel B, Rindler E, Fiorino A, Zaman TM, Sax, PE, Graeme-Cook F, Hibberd PL. Hepatic steatosis is associated with fibrosis, nucleoside analogue use and hepatitis C genotype 3 infection in HIV-sero-positive patients. Clinical Infectious Diseases, 2006; 43:365-72.

Fu LY, Ruthazer R, Wilson I, Patel A, Fox LM, Tuan TA, Jeena P, Chisaka N, Hassan M, Lozano J, Maulen-Radovan, I Thea DM, Qazi S, Hibberd P. Brief Hospitalization and Pulse Oximetry for Predicting Amoxicillin Treatment Failure in Children with Severe Pneumonia. Pediatrics Pediatrics 2006; 118; e1822-e1830 (doi:10.1542/peds.2005-2673) .