Adjunct Assistant Professor
VA Outpatient Clinic
Dept. Psychiatry Service
251 Causeway Street
Boston, MA 02114
Phone: 617-248-1047
Email: Knapp.Clifford_m@boston.VA.gov

Research Interests:

Dr. Knapp is interested in the pharmacology of substance abuse, particularly the pharmacokinetics and clinical utility of antidepressents in patients with alcoholism and depression. He also has spent some time exploring the effect of benzodiazepines in humans with familial alcoholism.

Recent Publications:

Knapp CM, Foye MM, Ciraulo DA, Kornetsky C. The type IV phosphodiesterase inhibitors, Ro 20-1724 and rolipram, block the initiation of cocaine self-administration. Pharmacol Biochem Behav 62(1):151-8, 1999.

Streeter CC, Ciraulo DA, Harris GJ, Kaufman MJ, Lewis RF, Knapp CM, Ciraulo AM, Maas LC, Ungeheuer M, Szulewski S, Renshaw PF. Functional magnetic resonance imaging of alprazolam-induced changes in humans with familial alcoholism. Psychiatry Res 82(2):69-82, 1998.

Knapp CM, Kornetsky C. Low-dose apomorphine attenuates morphine-induced enhancement of brain stimulation reward. Pharmacol Biochem Behav 55(1):87-91, 1996.

Knapp CM, Kornetsky C. Bromocriptine, a D2 receptor agonist, lowers the threshold for rewarding brain stimulation. Pharmacol Biochem Behav 49(4):901-4, 1994.