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Associate
Professor
Depts. Urology and Pharmacology
Tufts University School of Medicine
136 Harrison Avenue
Boston, MA 02111
Phone: 617-636-6865
Email: Peter.Ofner@Tufts.edu
Research Interests:
Peter Ofner, Ph.D. is interested in the study of hormonal carcinogenesis
of the prostate linked to aging, with special emphasis on toxicant-
and aging-induced oxidative stress in the target organ. A second
research interest is to explore and document the many underresearched
effects of dehydroepiandosterone (DHEA) and androstenedione, which
can be purchased without prescription. In the Department of Pharmacology
and Experimental Therapeutics, he teaches toxicology and assists
with organizing the graduate student Journal Club. He is also a
facilitator of Problem-Based Learning (PBL) for first year medical
students.
Publications:
Ofner P, Nadeau MR, Vena RL, Leav I. Metabolism of estradiol and
estrone in organ cultures of dorsolateral and ventral prostate of
untreated and sex hormone-implanted rats. Steroids 57(2):50-5, 1992.
Ofner P, Bosland MC, Vena RL. Differential effects of diethylstilbestrol
and estradiol-17 beta in combination with testosterone on rat prostate
lobes. Toxicol Appl Pharmacol 112(2):300-9, 1992.
Lee KH, Ofner P. Reductive metabolism of 5 alpha-dihydrotestosterone
by rat ventral and dorsolateral prostate: kinetic parameters of
the enzymes. J Steroid Biochem 29(5):553-7, 1988.
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