Associate Professor
Depts. Biochemistry and Pharmacology
Tufts University School of Medicine
136 Harrison Avenue
Boston, MA 02111
Phone: 617-636-6884
Email: Nanette.Orme-johnson@Tufts.edu

Research Interests:

Dr. Orme-Johnson's research interests include the mechanisms of ACTH stimulation of steroid hormone production; and the mechanism of cytochrome P-450 catalyzed oxygenase reactions.

Recent Publications:

Hartigan, J.A., Green, E.G., Mortensen, R.M., Menachery, A., Williams, G.H., and OrmeJohnson, N.R. 1995. Comparison of protein phosphorylation patterns produced in adrenal cells by activation of cAMP-dependent protein kinase and Ca-dependent protein kinase. J. Steroid Biochem. Mol. Biol. 53:95-101.

Epstein, L.F., and Orme-Johnson, N.R. 1991. Regulation of steroid hormone biosynthesis: Identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells. J. Biol. Chem. 266:19739-19745.

Epstein, L.F., and Orme-Johnson, N.R. 1991. Acute action of luteinizing hormone on mouse Leydig cells: Accumulation of mitochondrial phosphoprotein and stimulation of testosterone synthesis. Mol. Cell. Endocrinol. 81:113-126.

Green, E.G., and Orme-Johnson, N.R. 1991. Inhibition of steroidogenesis in rat adrenal cortex cells by a threonine analog. J. Steroid Biochem. Mol. Biol. 40:421-429.