Education | General Research Interest | Selected Research Projects
Selected Publications
TCSVM Faculty 

Akram Da'darah
Research Assistant Professor
Department of Biomedical Sciences
Infectious Diseases
Phone: 508-887-4205
Fax: 508-839-7911
Email:akram.da_darah@tufts.edu 
Dept. URL: http://www.tufts.edu/vet/biomed/infectious_diseases.htm
Lab URL: Molecular Helminthology Lab

Education

PhD - Hamburg University, Germany - 1997
MSc - Yarmouk Univeristy, Jordan - 1992
BSc - Yarmouk University, Jordan - 1990

  • General Research Interest

    Molecular and cellular parasitology, vaccines, immunology.

    Selected Research Projects

    1. Host-Parasite interaction. This project investigates the interactions between schistosome parasites and their host. This will enhance our understanding of the mechanism(s) of the parasites survival in the host for several years.

    2. Vaccine development for schistosomiasis. This project will evaluate the potential use of surface parasites proteins as vaccine candidates against schistosome infections.

    Selected Publications

    1. Da’dara A.A. and Harn D.A. (2010) Elimination of helminth infection restores HIV-1C vaccine specific T cell responses independent of helminth-induced IL-10. Vaccine. 28(5):1310-1317.

    2. Wang Y., Da’dara A.A., Thomas P.G., and Harn D.A. (2010) Dendritic Cells activated by an anti-inflammatory agent induce CD4+ Th2 type responses without impairing CD8+ memory and effector CTL responses. Immunol. 129(3):406-417.

    3. Harn D.A. McDonald J. Atochina O. Da’dara A.A. (2009) Modulation of host immune responses by helminth glycans. Immunol. Rev. 230(1):247-57.

    4. Da'dara A.A. , Li Y.S., Xiong T., Zhou J., Williams G.M., McManus D.P., Feng Z., Yu X.L., Gray D., and Harn D.A. (2008) DNA-based vaccine protects against zoonotic schistosomiasis in water buffalo. Vaccine. 26(29-30):3617-25.

    5. Atochina O., Da’dara A.A., Walker M., and Harn D.A. (2008) The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophages in vivo. Immunol. 125(1):111-121, Epub: March 28, 20008.

    6. Da’dara A.A., Lautsch N., Dudek T., Novitsky V., Lee T.H., Essex M. and Harn D.A. (2006) Helminth infection suppresses T cell immune response to HIV-DNA-based vaccine in mice. Vaccine. 24(24):5211-9. [Epub 2006 Apr 18].

    7. Da’dara A.A. and Harn D.A. (2005) Efficacy of DNA vaccines against tropical parasitic diseases. Expert Reviews of Vaccine. 4(4):575-589.

     

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