Education | Laboratory Personnel | General Research Interest
Selected Publications
TCSVM Faculty

Jean M. Mukherjee
Assistant Professor
Department of Biomedical Sciences
Infectious Diseases
Phone: 508-887-4756
Fax: 508-839-7911
Email: jean.mukherjee@tufts.edu
Dept. URL: http://www.tufts.edu/vet/dbs/infectious_diseases/

Education

DVM - University of Minnesota College of Veterinary Medicine - 1996
PhD - Albert Einstein College of Medicine - 1992
MS - Albert Einstein College of Medicine - 1991
BA - Hamline University - 1989

Board Certification

Diplomate of the American College of Veterinary Microbiologists (DACVM)


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Laboratory Personnel

Karen Baldwin, Animal Specialist
Kwasi Ofori, Senior Research Technician

General Research Interest

Development of immune-based methods for diagnosis, therapy, and prevention of infectious and toxin mediated diseases of human, veterinary and/or zoonotic concern; animal model development; in vivo evaluation of candidate therapeutics; veterinary microbiology and parasitology.

Research Sponsor Interest

  • Privately Funded Research
  • Federally Funded Research
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Selected Publications

  1. Jeong, K., J. Mukherjee, A. Wiffin, P. Singh, S. Tzipori, A. Sheoran. 2011. “Biodistribution and Elimination Kinetics of Shiga Toxin 2 by Specific Human Monoclonal Antibodies in a Mouse Model.” Submitted.

  2. J. Mukherjee, C. McCann, K. Baldwin, K. Ofori, C. Taylor, J. Hill, C. Shoemaker, P. Harrison, S. Tzipori.  2011. “Sheep Monoclonal Antibodies Prevent Systemic Effects of Botulinum Neurotoxin A1.” Submitted.

  3. Brady, M.J., P. Radhakrishnan, H. Liu, L. Magoun, D. Robbins, J. Mukherjee, A. Donohue-Rolfe, S. Tzipori, and J.M. Leong. 2011. “Enhanced Actin Pedestal Formation by Host-Adapted Enterohemorrhagic Escherichia coli O157:H7.” In Preparation.

  4. J. Mukherjee, K. Baldwin, K. Ofori, B. R. Singh, S. Tzipori. 2011. “Evaluation of an Atoxic Botulinum Neurotoxin A1 Holotoxin as a Candidate Vaccine Antigen.” In Preparation.

  5. J. Mukherjee, K. Baldwin, C. McCann, K. Ofori, S. Tzipori. 2011. “Refinement of Botulinum Neurotoxin Assays.” In Preparation.

  6. T.Smiley, D.E. Akiyoshi, J. Mukherjee, M. Bhandari, S. Paudel, S. Mikota, G. Kaufman. 2010. “Development of a PCR Diagnostic Technique to Differentiate Mycobacterium Species in Elephants in Nepal.” In Preparation.

  7. Wilson, T.S., L. Spelman , M. Lukasik-Braum, J. Mukherjee, G. Kaufman, D.E. Akiyoshi, M. Cranfield.  2010. “Non-Invasive Saliva Collection Technique for Improved Health Monitoring of Free-Living Mountain Gorillas (Gorilla beringei beringei). Journal of Zoo and Wildlife Medicine 41(2):201-209.

  8. Sepulveda, J., J. Mukherjee, S. Tzipori, L. Simpson, C. Shoemaker. 2010. “Efficient serum clearance of botulinum neurotoxin using a pool of small antitoxin binding agents." Infection and Immunity 78(2):756-763.

  9. Sepulveda, J., J. Mukherjee, S. Tzipori, L. Simpson, C. Shoemaker. 2010. “Efficient serum clearance of botulinum neurotoxin using a pool of small antitoxin binding agents." Infection and Immunity 78(2):756-763.

  10. Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O’Donnell, S. Rich, A. Donohue-Rolfe, and S. Tzipori. 2002. “Production and Characterization of Protective Human Antibodies Against Shiga-Toxin 1 (Stx1).” Infection and Immunity 70(10):5896-5899.

  11. Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O’Donnell, S. Rich, A. Donohue-Rolfe, and S. Tzipori. 2002. “Human Stx2 Antibodies Prevent Systemic Complications of Escherichia coli 0157:H7 Infection.” Infection and Immunity 70(2):612-619.

  12. Mukherjee, J., M.D. Scharff, and A. Casadevall. 1995. "Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Enhance Fluconazole Efficacy." Antimicrobial Agents and Chemotherapy 39:1398-1405.

  13. Mukherjee, J., M.D. Scharff, and A. Casadevall. 1995. "Variable Efficacy of Passive Antibody Administration Against Diverse Cryptococcus neoformans Strains." Infection and Immunity 63:3353-3359.

  14. Mukherjee, J., G. Nussbaum, M.D. Scharff, and A. Casadevall. 1995. "Somatic Mutation Can Generate Differences in Specificity that Change the Protective Efficacy of Antibodies to Cryptococcus neoformans." Journal of Experimental Medicine 181:405-409.

  15. Mukherjee, J., L.S. Zuckier, M.D. Scharff, and A. Casadevall. 1994. "Therapeutic Efficacy of Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Alone and in Combination with Amphotericin B." Antimicrobial Agents and Chemotherapy 38:580-587.

  16. Mukherjee, J., L.-A. Pirofski, M.D. Scharff, and A. Casadevall. 1993. "Antibody-Mediated Protection in Mice with Lethal Intracerebral Cryptococcus neoformans Infection." Proceedings of the National Academy of Science (PNAS) 90:3636-3640.

  17. Mukherjee, J., A. Casadevall, and M.D. Scharff. 1993. "Molecular Characterization of the Humoral Responses to Cryptococcus neoformans Infection and Glucuronoxylomannan-Tetanus Toxoid Conjugate Immunization." Journal of Experimental Medicine 177:1105-1116.

 

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