Education | Laboratory Personnel | General Research Interest | Selected Research Projects
Research and Clinical Interests | Major Specialized Equipment Items Available | Selected Publications
TCSVM Faculty

Christopher M. Schonhoff
Research Assistant Professor
Department of Biomedical Sciences
Phone: 508-887-4357
Email: christopher.schonhoff@tufts.edu

Education
PhD - UMASS Medical School - 2000
BS - Boston College - 1992

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General Research Interests - Signaling by nitric oxide, liver physiology and livery pathophysiology

Research Sponsor Interest

  • Privately Funded Research
  • Federally Funded Research
  • Internationally Funded Research
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Selected Publications

  1. Schonhoff C.M., Matsuoka M., Tummala H., Johnson M.A., Estevez A.G., Wu R., Kamaid A., Ricart K.C., Hashimoto Y., Gaston B., Macdonald T.L., Xu Z., Mannick J.B.(2006). Aberrant S-nitrosylation in Amyotrophic Lateral Sclerosis. Proceedings of the National Academy of Sciences. 103(7): 2404-2409.

  2. Schonhoff, C.M., Gillin, H., Webster, C.R.L., and Anwer, M.S.  Protein kinase Cδ mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes.  Hepatology. 2008 Apr;47(4):1309-16.

  3. Mannick, J. B., and Schonhoff, C.M.  Measurement of Protein S-nitrosylation During Cell Signaling.  Methods in Enzymology. 2008.Vol. 440:231-42.  Nitric Oxide, Part F.

  4. Schonhoff, C.M., Thankey, K., Webster, C.R.L., Wakabayashi, Y., Wolkoff, A.W., and Anwer, M.S. Rab4 facilitates cAMP-stimulated bile acid uptake and NTCP translocation Hepatology. 2008. Nov;48(5):1665-70.

  5. Godoy LC, Muñoz-Pinedo C, Castro L, Cardaci S, Schonhoff CM, King M, Tórtora V, Marín M, Miao Q, Jiang JF, Kapralov A, Jemmerson R, Silkstone GG, Patel JN, Evans JE, Wilson MT, Green DR, Kagan VE, Radi R, Mannick JB.  Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells.  Proceeding of the National Academy of Sciences. 2009. 106(8): 2653-8.

  6. Schonhoff CM, Webster CR, Anwer MS.  Cyclic AMP stimulates Mrp2 translocation by activating p38{alpha} MAPK in hepatic cells.  Am J Physiol Gastrointest Liver Physiol. 2010 May;298(5):G667-74.

  7. Schonhoff CM, Yamazaki A, Hohenester S, Webster CR, Bouscarel B, Anwer MS.  PKC{epsilon}-dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line.  Am J Physiol Gastrointest Liver Physiol. 2009 Dec;297(6):G1259-67

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