Education | Laboratory Personnel | General Research Interest | Selected Research Projects
Research and Clinical Interests | Major Specialized Equipment Items Available | Selected Publications
TCSVM Faculty

Patrick Skelly
Assistant Professor
Department of Biomedical Sciences
Infectious Diseases
Phone: 508-887-4348
Fax: 508-839-7911
Email: patrick.skelly@tufts.edu
Dept. URL: http://www.tufts.edu/vet/biomed/infectious_diseases.htm
Lab URL: Molecular Helminthology Lab

Education
PhD - Australian National University, Canberra, Australia - 1986
BS - University College Dublin, Ireland - 1981

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General Research Interest
Parasitology, molecular and cellular helminthology

Research Sponsor Interest

  • Privately Funded Research
  • Federally Funded Research

Laboratory Personnel

  • Dr. Greice Krautz-Peterson, Research Associate
  • Dr. Zahra Faghiri, Postdoctoral Associate
  • Mr. David Mwai Ndegwa, Research Assistant
  • Ms. Rita Bhardwaj, Graduate Student

 

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Selected Research Projects

  1. Gene silencing in schistosomes using RNA interference (RNAi): This research project is designed to provide a simple, powerful and widely applicable protocol for suppressing gene expression in parasitic platyhelminths (schistosomes) using RNAi and thereby to facilitate functional schistosome genomics. http://www.tufts.edu/vet/biomed/infectious_diseases.htm

  2. Molecular and Cellular Biology of the Schistosome Surface: This project is designed to identify and characterize host-interactive parasite surface molecules with a view to testing them as vaccine candidates. Molecular Helminthology Lab

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Selected Publications

  1. Ndegwe, D., Krautz-Peterson, G and Skelly, PJ.  Protocols for gene silencing in schistosomes. Exp Parasit 2007, in press.

  2. Krautz-Peterson, G, Camargo, S, Huggel, K, Verrey, F, Shoemaker, CB, Skelly, PJ. Amino acid transport in schistosomes: characterization of the permease heavy chain SPRM1hc. J Biol Chem 2007, 282, 21767-21775.

  3. Krautz-Peterson, G and Skelly, PJ. Schistosoma mansoni: the dicer gene and its expression. Exp Parasit, 2007, in press.

  4. Krautz-Peterson, G, Radwanska, M, Ndegwa, N, Shoemaker CB, and Skelly, PJ. Optimizing gene suppression in schistosomes using RNA interference. Mol Biochem Parasitol, 2007; 153, 194-202.

  5. Skelly, PJ, and Wilson, RA. Making sense of the schistosome surface. Adv Parasitol, 2006; 63: p. 185-284.

  6. Keating, J, Wilson, RA, and Skelly, PJ. No overt cellular inflammation around intravascular schistosomes in vivo. J Parasitol, 2006; 6, 1365-1369.

 

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