Acacia Alcivar-Warren
Associate Professor
Department of Environmental and Population Health
Environmental and Comparative Genomics
Phone: 508-839-7970
Fax: 508-839-7091
Email: acacia.warren@tufts.edu
Department URL: Environmental and Comparative Genomics
Education
PhD - Iowa State University - 1987
MS - Iowa State University - 1983
DVM - Universidad de Guayaquil - 1979
Laboratory Personnel
Se Won Park, PhD candidate
Dawn Meola-Meehan, Senior Research Assistant
General Research Interest
Research interests in my laboratory focus on three topics. First, using the marine shrimp, Penaeus (Litopenaeus) vanname, as a model to understand genome (nuclear and mitochondrial DNA) and environmental interactions on animal performance, we are developing a genetic map (ShrimpMap to understand spawning capacity and early development of shrimp. Second, we are developing a database of expressed sequence tags (ESTs) from somatic and germinal cell tissues of shrimp at different stages of development to be used for genome-wide expression studies using microarrays. Finally, work is ongoing using ESTs to map sex-determining and disease-susceptibility genes in shrimp and horses.
Research Sponsor Interest
- Privately Funded Research
- Federally Funded Research
Selected Research Projects
Mapping QTL for resistance to viral diseases. International Marine Shrimp Genomics Initiative. Mitochrondrial mutations and gene expression. Mapping genes associated with sepsis in foals.
Research and Clinical Interests
Genomic and cDNA library construction
Selected Publications
Pascual I, Dhar AK, Fan Y, Paradis MR, Arruga MV, Alcivar-Warren A. Isolation of expressed sequence tags from a Thoroughbred horse (Equus caballus) 5'-RACE cDNA library. Animal Genetics 33(3):231-232, 2002.
Dhar, A.K., M.S. Thompson, M.R. Paradis and A. Alcivar-Warren. 2000. Determination of the cDNA sequence and mRNA expression of interleukin1 receptor antagonist in horses. American Journal of Veterinary Research 61: 920-924.
Xu Z, Primavera JH, de la Pena LD, Pettit P, Belak J, Alcivar-Warren A. 2001. Genetic diversity of wild and cultured Black Tiger Shrimp (Penaeus monodon) in the Philippines using microsatellites. Aquaculture 199:13-40.
Meehan, D., Z. Xu, G. Zuniga and A. Alcivar-Warren. 2002. Polymorphic microsatellites in Penaeus (litopenaeus) vannamei. Marine Biotechnology. In press.
Alcivar-Warren, A., Z. Xu, D. Meehan, Y. Fan and L. Song. 2002. Shrimp genomics: development of a genetic map to identify QTLs responsible for economically important traits in Litopenaeus vannamei. Nobuyoshi Shimizu, Takashi Aoki, Ikuo Hirono, Fumio Takashima (Eds.), In: Aquatic Genomics: Steps Toward a Great Future. Springer-Verlag, Tokyo, Japan, pp.61-72.