Education | Laboratory Personnel | General Research Interest | Selected Research Projects
Research and Clinical Interests | Major Specialized Equipment Items Available | Selected Publications
TCSVM Faculty

Giovanni Widmer
Professor
Department of Biomedical Sciences
Infectious Diseases
Phone: 508-839-7944
Fax: 508-839-7911
Email: giovanni.widmer@tufts.edu
Dept. URL: http://www.tufts.edu/vet/biomed/infectious_diseases.htm
Lab URL: Giardia, Cryptosporidium Testing Services

Education
PhD - London School of Hygiene and Tropical Medicine - 1986

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General Research Interest
Molecular biology of protozoan parasites
Waterborne pathogens

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Research Sponsor Interest
Privately Funded Research
Federally Funded Research

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Selected Research Projects

  1. Genetics of Cryptosporidium parvum
  2. Functional genomics of Cryptosporidium parvum
  3. A high-throughput screen for enhancers of Cryptosporidium parvum in vitro growth
  4. Cryptosporidium muris genome sequencing
  5. Acoustic cavitation against biological threats
  6. Determination of Cryptosporidium occurrence, infectivity, and genotyping in wastewater effluents

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Selected Publications

  1. Garcia A, Walker W, Yanko W, Batzer G, Widmer G. (2002) Removal and fate of Giardia cysts in water reclamation plants. Water Environ. Res. 74,541-4..

  2. Widmer G, Clancy T, Ward HD, Miller D, Batzer GM, Pearson CB, Bukhari Z. (2002) Structural and biochemical alterations in Giardia lamblia cysts exposed to ozone. J. Parasitol. 88,1100-6.

  3. Tanriverdi S, Arslan MÖ, Akiyoshi DE, Tzipori S, Widmer G (2003) Identification of genotypically mixed Cryptosporidium parvum populations in humans and calves. Molec Biochem Parasitol. 130,13-22.

  4. Widmer G. (2004) Population genetics of Cryptosporidium parvum. Trends Parsitol. 20,3-6.

  5. Abrahamsen MS, Templeton TJ, Enomoto S, Abrahante JE, Zhu G, Lancto CA, Deng M, Liu C, Widmer G, Tzipori S, Buck GA, Xu P, Bankier AT, Dear PH, Konfortov BA, Spriggs HF, Iyer L, Anantharaman V, Aravind L, Kapur V. (2004) Complete genome sequence of the Apicomplexan, Cryptosporidium parvum. Science 304,441-5.

  6. Xu P, Widmer G, et al. (2004) The Genome of Cryptosporidium hominis. Nature 431,1107-12.

  7. Johnson AM, Linden K, Ciociola KM, DeLeon R, Widmer G, Rochelle P (2005) UV inactivation of Cryptosporidium hominis as measured in cell culture. Appl. Environ. Microbiol. 71,2800-2.

  8. Tanriverdi S, Widmer G. (2006) Differential evolution of repetitive sequences in Cryptosporidium parvum and Cryptosporidium hominis. Infect. Genet. Evol. 6,113-22

  9. Tanriverdi S, Markovics A, Arslan MÖ, Itik A, Shkap V, Widmer G. (2006) Emergence of distinct genotypes of Cryptosporidium parvum in structured host populations. Appl. Environ. Microbiol. 72,2507-2513.

  10. Widmer G, Yang YL, Bonilla R, Tanriverdi S, Ciociola K (2006) Preferential infection of dividing cells by Cryptosporidium parvum. Parasitology 133,131-8.

  11. Huffman DE, Gennaccaro AL, Berg TL, Batzer G, Widmer G. (2006) Detection of infectious parasites in reclaimed water. Water Env Res 78,2297-302.

  12. Feng, X., Akiyoshi D., Sheoran AS., Singh I., Hanawalt J., Zhang Q., Widmer G., Tzipori S. (2006) Serial propagation of the microsporidium Enterocytozoon bieneusi of human origin in rodents. Infect. Immun. 74,424-9.

  13. Chappell CL, Okhuysen PC, Langer-Curry R, Widmer G., Akiyoshi DE, Tanriverdi S, and Tzipori S. (2006) Cryptosporidium hominis: Experimental challenge of healthy adults. Am. J. Trop. Med. Hyg. 75,851-7.

  14. Tanriverdi S, Blain JC, Deng B, Ferdig M, Widmer G (2007) Genetic crosses in the apicomplexan parasite Cryptosporidium parvum define recombination parameters. Mol. Microbiol. 63,1432-9.

  15. Grinberg A, Lopez-Villalobos N, Pomroy W, Widmer G, Smith HW, Tait A. (2007) Host-shaped segregation of the Cryptosporidium parvum multilocus genotype repertoire. Epidemiol Infect 136,273-8

  16. Tanrιverdi S, Blain JC, Deng B, Ferdig M, Widmer G (2007) Genetic crosses in the apicomplexan parasite Cryptosporidium parvum define recombination parameters. Molec. Microbiol. 63,1432-9.

  17. Bean CL, Hansen JJ, Margolin AB, Balkin H, Batzer G, Widmer G (2007) Class B alkaline stabilization to achieve pathogen inactivation. Int. J. Environ. Res. Publ. Health 4,53-60.

  18. Widmer G, Klein P, Bonilla R (2007) Adaptation of Cryptosporidium oocysts to different excystation conditions. Parasitology 134,1583-8.

  19. Feng X, Akiyoshi DE, Widmer G, Tzipori S (2007) Characterization of subtilase protease in Cryptosporidium parvum and C. hominis. J. Parasitol. 93,319-26.

 

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