TCSVM Faculty

Giovanni Widmer
Professor
Department of Infectious Disease and Global Health
Phone: 508-839-7944
Fax: 508-839-7911
Email: giovanni.widmer@tufts.edu
Dept. URL: http://www.tufts.edu/vet/dbs/infectious_diseases/
Lab URL: Giardia, Cryptosporidium Testing Services

Education
PhD - London School of Hygiene and Tropical Medicine - 1986

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General Research Interest
Molecular biology of protozoan parasites
Waterborne pathogens

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Research Sponsor Interest
Privately Funded Research
Federally Funded Research

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Selected Research Projects

  1. Genetics of Cryptosporidium parvum.
  2. Cryptosporidium genome sequencing.
  3. Detection and genotyping of Cryptospordium oocysts and Giardia cysts in water.
  4. Analysis of complex microbial populations using high-throughput sequencing.

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Selected Publications

  1. Zhang Q, Widmer G, Tzipori S (2013) A pig model of the human gastro-intestinal tract. Gut Microbes (in press).

  2. Widmer G, Lee Y, Hunt P, Martinelli A, Tolkoff M, Bodi K (2012) Comparative genome analysis of two Cryptosporidium parvum isolates with different host range. Infect Genet Evol 12,1213-21.

  3. Ben Ayed L, Yang W, Widmer G, Cama V, Ortega Y, Xiao L (2012) Survey of wastewater in Tunisia for Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi, Cyclospora cayetanensis and Eimeria spp. J Water Health 10,431-44.

  4. Herges G, Widmer G, Clark M, Khan E, Giddings C, Brewer M, McEvoy J (2012) Evidence that Cryptosporidium parvum populations are panmictic and unstructured in the Upper Midwest United States. (2012) Appl Environ Microbiol 78,8096-101.

  5. Sheoran A, Wiffin A, Widmer G, Tzipori S (2012) Infection with Cryptosporidium hominis provides incomplete protection of the host against C. parvum. J Infect Dis 205,1019-23. PMID:22279124.

  6. Drumo R, Widmer G, Morrison L, Tait A, Grelloni V, D'Avino N, Pozio E, Cacciò S (2012) Population genetics of Cryptosporidium parvum in Italy: evidence of host-associated populations. Appl Environ Microbiol (in press) PMID:22389374.

  7. Chappell C, Okhuysen P, Langer-Curry R, Akiyoshi D, Widmer G, Tzipori S (2011) Cryptosporidium meleagridis: infectivity in healthy adult volunteers. Am J Trop Med Hyg 85,238-42.

  8. Widmer G, Sullivan S (2011) Genomics and population biology of Cryptosporidium species (Review). Parasite Immunol. May 19. doi: 10.1111/j.1365-3024.2011.01301.

  9. Faghiri Z, Bonilla Santiago R, Wu Z, Widmer G (2011) High-throughput screening in sub-optimal growth conditions identifies agonists of Giardia lamblia proliferation. Parasitology, 138, 194-200.

  10. Widmer G, Lee Y. (2010) Comparison of single- and multi-locus genetic diversity in the protozoan parasites Cryptosporidium parvum and C. hominis. Appl Environ Microbiol. 76,6639-44. PMID: 20709840.

  11. Faghiri Z, Santiago RB, Wu Z, Widmer G. High-throughput screening in suboptimal growth conditions identifies agonists of Giardia lamblia proliferation. Parasitology. (2010) Aug 10:1-7. [Epub ahead of print] PubMed PMID: 20696097.

  12. Yang YL, Buck GA, Widmer G (2010) Cell sorting-assisted microarray profiling of host cell response to Cryptosporidium parvum infection. Infect Immun 78(3):1040-8. PubMed PMID: 20038534.

  13. Widmer G, Akiyoshi D. (2010) Host specific segregation of ribosomal nucleotide sequence diversity in the microsporidian Enterocytozoon bieneusi. Infect Genet Evol 10(1):122-8 PMID:19931647.

 

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