Evaluating the alangesic effect of a daily dose of methadone. Subjects given both placebo and methadone, in random order, in a double blind fashion. Outcome: measure of maximum pain (0=none, 100=severe) on placebo (Plac) or methadone (Meth). Is there sufficient evidence to conclude at the 0.05 level of signifcance that methodone lowers the intensity of pain?