Title: Options for Shape and Multi-parameter Inverse Problems Speaker: Eric Miller Affiliation: ECE Dept., Tufts University Abstract: The desire to extract information concerning the internal structure of a medium based upon data collected only at the periphery is a problem encountered across a broad range of technical fields and application areas ranging from medical imaging and nondestructive evaluation to geophysical exploration and environmental remediation. The goal of this talk is to discuss a number of modeling and estimation options associated with two subsets of such inverse problems that have been receiving increased attention in recent years. First, we present ideas concerning the recovery of shape information in an inverse problems context. Rather than seeking to use limited and noisy data to recover the values of a large number of pixels in a region of interest, the goal of a shape-based approach to imaging is the estimation of the geometric structure of anomalous objects (tumors, cracks, regions of functional brain activity, ...) located in a perhaps uncertain background. While level set methods have garnered significant attention in recent years for their ability to identify even an unknown number of objects, these techniques can be slow to converge and are far from trivial to implement. In the first portion of this talk, we introduce a new approach to modeling shape that possesses much of the topological flexibility of level sets but with fewer of the drawbacks. In the second portion of the talk, we focus on the issues of recovering multiple parameters of the medium from perhaps multiple sets of data. In the geophysical context, for example, one may wish to characterize the structure of reservoir from electromagnetic as well as seismic data in which case one seeks information concerning the electromagnetic and acoustic properties of the medium. In the case of breast imaging for cancer screening, there is wide interest in fusing information from multiple sensors (x-ray, electrical impedance, diffusion optical, etc) to develop a coherent picture of the state of the breast. In these and other cases, the goal of reconstructing multiple parameters tends to exacerbate the ill-posedness of the associated inverse problem. Here then we discuss a couple of options for regularizing such problems. The first building on the parametric level set ideas to achieve regularization via geometry. The second approach is appropriate for pixel-based inversions and is based on the development of regularizing functionals that in some sense enforce "similarity" across the multiple parameters.